医学免疫学 (印度)苏尼尔 . 库马尔 . 莫汉蒂(印度)K . 赛 . 利拉

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作者: (印度)苏尼尔 . 库马尔 . 莫汉蒂(印度)K . 赛 .
出版社: 清华大学出版社
ISBN: 9787302463085
出版时间: 2017-02
版次: 1

装帧: 平装
开本: 16开
纸张: 胶版纸
页数: 204页
字数: 99999千字

作者: (印度)苏尼尔 . 库马尔 . 莫汉蒂(印度)K . 赛 .
出版社: 清华大学出版社
ISBN: 9787302463085
出版时间: 2017-02

版次: 1
装帧: 平装
开本: 16开

纸张: 胶版纸
页数: 204页
字数: 99999千字

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书名:医学免疫学
定价：99.8元
作者:(印度)苏尼尔 . 库马尔 . 莫汉蒂(印度)K . 赛 . 利拉
出版社：清华大学出版社
出版日期：2017-02-01
ISBN：9787302463085
字数：517000
页码：204
版次：1
装帧：平装
开本：16开
商品重量：
编辑推荐
正版原版，原汁原味，留学生与双语教学用。
内容提要
医学免疫学是一门独立的学科，是研究免疫系统的组织结构和功能的科学。它从不同的角度和水平来揭示免疫系统识别并消除抗原性异物的应答过程和规律，并应用这些规律来阐明免疫相关疾病发生发展的机制，达到防治相关疾病的目的。医学免疫学进展迅速，知识量大，本教材基于很基本的理论和知识，介绍了抗原、免疫器官和免疫细胞、免疫分子（抗体、补体、细胞因子、黏附分子和 MHC等）、免疫应答、免疫预防、免疫治疗、免疫诊断、免疫耐受、免疫相关疾病以及感染免疫等。本教材适用于医学专业外国留学生的医学免疫学英文教学和本科双语教学。
目录
Chapter 1Introduction......................................... 1A BRIEF OVERVIEW OFIMMUNOLOGY................. 1HIST ORY OFIMMUNOLOGY................................... 10STUDY QUESTIONS....................................................13Suggested readingS.......................................... 13Chapter 2Antigen.................................................... 14DEFINITION.................................................................14Epitopes......................................................................14Classification of Antigens BASED ONIMMUNERESPONSE............................................. 15DETERMINANTS OF IMMUNOGENICITY............15ANTIGENRECEPTORS.............................................. 16ANTIGENICSPECIFICITY......................................... 17STUDY QUESTIONS................................................... 18SuggestedreadingS........................................... 18Chapter 3 Antigen Recognition Molecules.......................................................................19ANTIBODIES—IMMUNOGLOBULINS...................20Major Histocompatibility Complex .........25STUDY QUESTIONS....................................................28SuggestedReadingS........................................... 28Chapter 4 The Complement System............29ComplementActivation................................. 29Regulation of the ComplementSystem .................................................................31Biological Consequences ofComplementActivation.............................. 32Defects in the Complement System...........34STUDY QUESTIONS................................................... 34SuggestedreadingS........................................... 35Chapter 5 Organs and Tissues of theImmuneSystem................................. 36LYMPHOIDORGANS................................................. 36ContentsSTUDY QUESTIONS....................................................39SuggestedReadingS........................................... 39Chapter 6 ImmuneCells...................................... 41Lymphocytes...........................................................41PhagocyticCells................................................. 47Dendritic Cells.................................................... 48STUDYQUESTIONS.................................................... 48Suggested ReadingS...........................................48Chapter 7 ImmuneResponse............................ 49AN TIGEN PROCESSING ANDPRESENTATION...................................................49AC TIVATION OF HELPER TLYMPHOCYTES.......... 51HU MORAL IMMUNE RESPONSE(HUMORAL IMMUNITY)....................................55PRIMARY AND SECONDARY RESPONSE ...........58FA CTORS INFLUENCING ANTIBODYPRODUCTION........................................................59CE LL-MEDIATED IMMUNE RESPONSE(CELL-MEDIATED IMMUNITY)..........................60CYTOKINES..................................................................64THEORIES OF IMMUNERESPONSE....................... 71STUDYQUESTIONS.................................................... 73SUGGESTED READINGS...........................................75Chapter 8 ImmunologicalTolerance........... 76CE NTRAL T CELL TOLERANCE TOSELFANTIGENS...............................................................76PE RIPHERAL T CELL TOLERANCE TOSELFANTIGENS...............................................................77B C ELL TOLERANCE TOSELF-ANTIGENS........... 78AR TIFICIALLY INDUCED TOLERANCE INVIVO.........................................................................79STUDY QUESTIONS....................................................80SUGGESTEDREADINGS........................................... 80Contents目录XIV 医学免疫学MeeddiiccaallIImmuunnoollooggyyChapter 9Hypersensitivity................................ 81DEFINITION.................................................................81GELL AND COOMBSCLASSIFICATION................ 81IMMEDIATE TYPE IHYPERSENSITIVITY.............. 81TY PEⅡ HYPERSENSITIVITYREACTION(ANTIBODY-DEPENDENT CYTOTOXICITY)........89TY PEⅢ HYPERSENSITIVITY REACTION(IMMUNECOMPLEX-MEDIATED).................... 93TY PE Ⅳ CELL-MEDIATED(DELAYED)HYPERSENSITIVITY..............................................96STUDYQUESTIONS.................................................. 101SUGGESTED READINGS.........................................101Chapter 10Autoimmunity................................ 102PR OBABLE MECHANISMS OFAUTOIMMUNITY................................................102AUTOIMMUNEDISEASES...................................... 107STUDY QUESTIONS..................................................109Suggestedreadings......................................... 110Chapter 11 Immunodeficiency Disorders......111PRIMARYIMMUNoDeFICIENCIES...................... 111SE CONDARY (ACQUIRED) IMMUNodEFICIENCIES..................................................................................117STUDYQUESTIONS.................................................. 125SUGGESTEDREADINGs......................................... 125Chapter 12 Tumor Immunology.........................126CANCER:ORIGIN..................................................... 126TUMORANTIGENS.................................................. 129CancerImmunotherapy................................ 134STUDY QUESTIONS..................................................136SUGGESTEDREADINGs......................................... 137Chapter 13 Transplantation Immunology......138GraftRejection................................................... 138FACTORS FAVORINGALLOGRAFT SURVIVAL......140Mechanism Involved in Graft Rejection................................................................................142Tempo ofRejection............................................ 145STUDYQUESTIONS.................................................. 147SUGGESTEDREADINGS......................................... 147Chapter 14 ImmunologicalTechniques.......... 149ST AGES OF ANTIGEN-ANTIBODYINTERACTIONS....................................................149ME ASUREMENT OF ANTIGEN AND ANTIBODY................................................................................149PrecipitationReactions.................................149AgglutinationReaction............................. 154MO NOCLONAL ANTIBODIES ANDHYBRIDOMATECHNIQUE............................. 167STUDYQUESTIONS.................................................. 170SUGGESTEDREADINGs......................................... 171Chapter 15 Immunoprophylaxis &Immunotherapy...............................172IMMUNOPROPHYLAXIS........................................172IMMUNOTHERAPY..................................................179STUDYQUESTIONS.................................................. 183SUGGESTEDREADINGs......................................... 183Chapter 16 Immunity in Viral, Bacterial,Fungal, and ParasiticInfections.............................................184IMMU NITY INVIRALINFECTIONS...................... 184IMMU NITY IN BACTERIALINFECTIONS........... 188IMMU NITY IN FUNGALINFECTIONS................ 197IMMU NITY IN PARASITICINFECTIONS............ 198STUDYQUESTIONS.................................................. 204SUGGESTEDREADINGs......................................... 204
作者介绍
姚智，教授现任天津医科大学基础医学院免疫学系主任、天津医科大学病原生物与免疫学学科学术带头人、天津医科大学党委书记等职务。任第十七届世界支原体联盟常务理事，中华微生物学及免疫学会主任委员，中国免疫学会理事，中国医药生物技术协会临床应用委员会常务理事，中国细胞生物学与分子生物学学会临床分会常务理事，中华医学会天津分会检验学会主任委员等学术职务。任中国检验医学杂志英文版主编，中国免疫学杂志编委，中国肿瘤临床（英文版）编委，中草药编委等植物。曾获天津市教书育人十大标兵、天津市卫生系统科技优选个人；他领导的课题组获天津市卫生系统科技优选集体、天津市“十五”立功优选集体；天津市“五一”立功优选集体，他本人荣获天津市“八五”“九五”“十五”立功奖章、天津市劳动模范、天津市科技明星、天津市第四届青年科技奖；为国务院特殊津贴专家；天津市“131工程”人才培养靠前层次人选；卫生部有突出贡献中青年专家；天津市授衔专家；2006年入选“新世纪百千万人才工程”重量人选。
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